Hypertrophic osteopathy secondary to an extrathoracic disease (transitional cell carcinoma)

report of a case

Abstract

Hypertrophic osteopathy (OH) is a generalized osteoproductive disorder of the periosteum that affects the long bones of the limbs, observed mainly in humans and canines. It occurs in response to a pathology in another region of the body. In dogs, OH is more commonly diagnosed as a response to an intrathoracic disease. The objective of the present study was to describe the clinical diagnosis and evolution from a case of hypertrophic osteopathy secondary to a tumor of transitional cells of the bladder. The patient, canine, female, medium-sized (30 kg), 10 years old, had hematuria of 4 months of evolution. In the clinical examination, an increase in the thickness of the distal third of the extremities was observed with areas of non-painful swelling, of firm to hard consistency. Radiographs of the anterior extremities show inflammation of the soft tissues at the carpus level, the periosteal reaction with bone neoformation of the mixed pattern in the ulna and the distal radius and laminar in the metacarpus, compatible with OH. Ultrasound showed bladder neoformation of 8.2 x 6.5 cm, irregular and irrigated. Histopathological diagnosis confirmed a transitional cell tumor carcinoma.