Leukocyte and platelet rich fibrin for the treatment of oronasal fistula in canines

Authors

  • Agustina Algorta Servicio de Odontoestomatología, Centro Hospital Veterinario, Facultad de Veterinaria, Universidad de la República. Unidad de Inmunología e Inmunoterapia, Departamento de Patobiología, Facultad de Veterinaria, Universidad de la República. Autora para correspondencia: agustinaalgorta@gmail.com https://orcid.org/0000-0002-5214-8002
  • Carolina Semiglia Servicio de Odontoestomatología, Centro Hospital Veterinario, Facultad de Veterinaria, Universidad de la República https://orcid.org/0009-0008-5683-9063
  • Manuela Constantin Servicio de Odontoestomatología, Centro Hospital Veterinario, Facultad de Veterinaria, Universidad de la República https://orcid.org/0009-0009-4673-8231
  • María Noel Glausiuss Servicio de Odontoestomatología, Centro Hospital Veterinario, Facultad de Veterinaria, Universidad de la República. https://orcid.org/0009-0001-1082-1019
  • Juan Martín Eguren Servicio de Odontoestomatología, Centro Hospital Veterinario, Facultad de Veterinaria, Universidad de la República. Unidad de Cirugía y Anestesia de Pequeños Animales, Departamento de Clínicas y Hospital Veterinario, Facultad de Veterinaria, Universidad de la República. https://orcid.org/0000-0003-1121-7101
  • Gabriela Turini Servicio de Odontoestomatología, Centro Hospital Veterinario, Facultad de Veterinaria, Universidad de la República. https://orcid.org/0000-0001-5348-8001
  • Kevin Yaneselli Unidad de Inmunología e Inmunoterapia, Departamento de Patobiología, Facultad de Veterinaria, Universidad de la República. https://orcid.org/0000-0002-4602-5698

DOI:

https://doi.org/10.29155/VET.61.223.8

Keywords:

Periodontal disease, Veterinary dentistry, Blood products

Abstract

Platelet-rich fibrin (L-PRF) is a second-generation blood derivative that can be utilized as a biological filler due to the dense fibrin network formed, acting as a scaffold for cells and sustained release of growth factors, aiding in wound healing. In this study, two clinical cases presented at the Odontostomatology Service of the Veterinary School, UDELAR, involving patients with oro-nasal fistula (ONF) were evaluated. The affected tooth was extracted, and ONF closure was achieved using a mucoperiosteal flap and placement of L-PRF in the tooth socket to promote healing. Favorable outcomes were observed during postoperative follow-ups at days 7, 14, and 30, with complete closure and no complications or recurrences in both clinical cases. In these cases, the use of L-PRF placed with the mucoperiosteal flap was able to withstand oral mechanical forces, with no suture dehiscence or ONF recurrence, resulting in satisfactory healing. The use of this regenerative technique appears to offer a new approach for alveolar defect closure, with advantages including its speed, cost-effectiveness, simplicity, ease of implementation in a veterinary clinic, safety, and low risk.

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Published

2025-05-20

How to Cite

Algorta, A., Semiglia, C., Constantin, M., Glausiuss, M. N., Eguren, J. M., Turini, G., & Yaneselli, K. (2025). Leukocyte and platelet rich fibrin for the treatment of oronasal fistula in canines. Veterinaria (Montevideo), 61(223), e20256122308. https://doi.org/10.29155/VET.61.223.8

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Section

Technical Notes

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